Cathepsins: Proteases that are vital for survival but can also be fatal

“Not Everything That Is Faced Can Be Changed, but Nothing Can Be Changed Until It Is Faced”: A Response to Recent Commentaries

How confident can we be that orthologs are similar, but paralogs differ?

Homologous genes are classified into orthologs and paralogs, depending on whether they arose by speciation or duplication. It is widely assumed that orthologs share similar functions, whereas paralogs are expected to diverge more from each other. But does this assumption hold up on further examination? We present evidence that orthologs and paralogs are not so different in either their evolutio...

Recursive Path Orderings Can Also Be Incremental

In this paper the Recursive Path Ordering is adapted for proving termination of rewriting incrementally. The new ordering, called Recursive Path Ordering with Modules, has as ingredients not only a precedence but also an underlying ordering =B. It can be used for incremental (innermost) termination proofs of hierarchical unions by defining =B as an extension of the termination proof obtained fo...

First impressions are good, but appearances can be deceptive!

Zahn et al. publish the latest analyses from the Carotid Artery Stent (CAS) Registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausartzte (ALKK) of Germany. This reports outcomes following CAS in octogenarians (n 1⁄4 321) compared with younger patients (n 1⁄4 2557). As indicated in the introduction, this analysis was prompted by conflicting published data regarding the safety of...

Ancient Food Habits Dictate that Food Can Be Medicine but Medicine Cannot Be “Food”!!

Background: Extensive surveys of several population settlements in different parts of India-covering plains, mountains, valleys, river banks and deeper areas of forests at different altitudes-between 1968 and 2016 demonstrated that the basic vital need of hunger is being fulfilled since antiquity by plants in the wild. Methods: Based on collections, consultations with local population personnel...